ER Cast: Then And Now

By Ryan Schwartz
ER - Season 1 Cast Photo Everett Collection

ER was a pivotal piece of NBC's Must-See TV lineup from 1994-2009, airing Thursdays at 10/9c for the entirety of its run. It amassed a record-setting 124 Emmy nominations, winning a total of 23 Emmys, including one for Outstanding Drama Series.

On Thursday, April 22, the original cast (along with a few later additions) will come together for a virtual reunion — which you catch watch here.

Up until 2019, when it was upstaged by ABC's Grey's Anatomy, ER's 331 episodes made it TV's longest-running medical drama. While a revival is not currently in the works, executive producer John Wells has said that he'd be open to a revival if "a really interesting idea" came along.

Scroll down to see photos of the series' original six cast members, then and now...

ER Cast - Then and Now

ER Cast - Then and Now Everett Collection; Andy Kropa/Invision/AP

Anthony Edwards (Mark Greene)

Seasons 1-8 (series regular); Season 15 (guest star)

ER Cast - Then and Now

ER Cast - Then and Now Everett Collection; Willy Sanjuan/Invision/AP

George Clooney (Doug Ross)

Seasons 1-5 (series regular); Seasons 6, 15 (guest star)

ER Cast - Then and Now

ER Cast - Then and Now Everett Collection (2)

Sherry Stringfield (Susan Lewis)

Seasons 1-3, 8-12 (series regular); Season 15 (guest star)

ER Cast - Then and Now

ER Cast - Then and Now Everett Collection; Sthanlee B. Mirador/Sipa via AP Images

Noah Wyle (John Carter)

Seasons 1-11, 15 (series regular); Season 12 (guest star)

ER Cast - Then and Now

ER Cast - Then and Now Everett Collection; Joseph Marzullo/MediaPunch/IPX

Julianna Margulies (Carol Hathaway)

Seasons 1-6 (series regular); Season 15 (guest star)

ER Cast - Then and Now

ER Cast - Then and Now Everett Collection; Charles Sykes/Invision/AP

Eriq La Salle (Peter Benton)

Seasons 1-8 (series regular); Season 15 (guest star)

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