The Big Bang Theory Turns 15: The 23 Best Sheldon-And-Amy Moments — Including One From Young Sheldon

Remember when The Big Bang Theory's Sheldon would only refer to Amy as his friend but not his girlfriend? Eight years later, the fan-favorite couple said "HIja'!" (That's "I do" in Klingon.)

Sheldon and Amy's wedding was also where they made their initial breakthrough in super asymmetry, which earned them a Nobel Prize in the 2019 series finale. 

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In honor of Big Bang's 15th anniversary, TVLine is looking back at 23 unforgettable moments that showcase the evolution of #Shamy — including, but not limited to: their peculiar meet-cute, a devastating break-up and a cross-country proposal. We've also included all of their firsts, such as the first time they held hands and, yes, the first time they had coitus. We've also included a moment from the prequel series Young Sheldon, which offer a glimpse into the fan-favorite couple's future. All are available to stream on HBO Max (sign up here).

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Keep scrolling to see which moments made our cut, then hit the comments and tell us if you agree (or disagree) with our choices.

Meet Cute in 'The Lunar Excitation'

Season 3, Episode 23

Original Airdate: May 24, 2010

The pair bond over their nagging mothers, then Sheldon offers to buy her a warm beverage. The rest is history.

First Date in 'The Robotic Manipulation'

Season 4, Episode 1

Original Airdate: Sept. 23, 2010

Penny serves as chaperone. Suffice it to say, the #Shamy heat is not yet palpable.

Holding Hands in 'The Alien Parasite Hypothesis'

Season 4, Episode 10

Original Airdate: Dec. 9, 2010

Amy poses an "experiment," but feels nothing. That'll change.

First Kiss in 'The Agreement Dissection'

Season 4, Episode 21

Original Airdate: April 28, 2011

Dr. Fowler may be drunk, but it still marks a significant step forward in their relationship.

Assigning Labels in 'The Flaming Spittoon Acquisition'

Season 5, Episode 10

Original Airdate: Nov. 17, 2011

Once opposed to labels, Sheldon gives in and offers Amy the chance to "alter the paradigm of their relationship." They are hereby known as boyfriend and girlfriend.

Amy Is a Princess in 'The Shiny Trinket Maneuver'

Season 5, Episode 12

Original Airdate: Jan. 12, 2012

"Ohhhhhhhhh, it's a tiara! Put it on me! Put it on me!" Need we say more?

Holding Hands (For Real) in 'The Countdown Reflection'

Season 5, Episode 24

Original Airdate: May 10, 2012

This time it's no experiment. As he watches Howard journey towards outerspace, Sheldon reaches for his girlfriend's hand and doesn't let go.

First Spanking in 'The Fish Guts Displacement'

Season 6, Episode 10

Original Airdate: Dec. 6, 2012

Dr. Fowler has been "a very bad girl," and Dr. Cooper has no choice but to "punish" her.

In Case of Emergency in 'The Tangible Affection Proof'

Season 6, Episode 16

Original Airdate: Feb. 14, 2013

Sheldon isn't ready to move in with Amy, but he is willing to entrust her with his well-being should he fall violently ill at work. So, he makes her his emergency contact.

First Roleplay in 'The Love Spell Potential'

Season 6, Episode 23

Original Airdate: May 9, 2013

Who needs physical intimacy when you can partake in a cheeky game of Dungeons & Dragons?

First Kiss (For Real) in 'The Locomotive Manipulation'

Season 7, Episode 15

Original Airdate: Feb. 6, 2014

Sheldon kisses a girl... and he likes it! Best. Valentine's Day. Ever.

First I Love You's in 'The Prom Equivalency'

Season 8, Episode 8

Original Airdate: Nov. 6, 2014

Sheldon isn't ready for a certain prom-night tradition, but he is ready to tell Amy just how much she means to him.

The Breakup in 'The Commitment Determination'

Season 8, Episode 24

Original Airdate: May 7, 2015

Convinced that their five-year relationship is going nowhere fast, Amy ends things altogether. Little does she know that Sheldon has an engagement ring sitting in his desk drawer.

Amy Gets the Red Light in 'The Platonic Permutation'

Season 9, Episode 9

Original Airdate: Nov. 19, 2015

Sheldon tells Amy that he can't bear the thought of having to get over her again, so he rejects her offer to resume dating.

Kiss and Make Up in 'The Earworm Reverberation'

Season 9, Episode 10

Original Airdate: Dec. 10, 2015

The brainiac barges in on Amy's date with Dave (sorry Dave!) and asks to be her boyfriend again.

First Coitus in 'The Opening Night Excitation'

Season 9, Episode 11

Original Airdate: Dec. 17, 2015

Sheldon and Amy have sex for the first time. Needless to say, this is one birthday Amy will never forget. 

First 'Sleepover' in 'The Cohabitation Experimentation'

Season 10, Episode 4

Original Airdate: Oct. 10, 2016

After moving in together, Sheldon makes it impossible for Amy to sleep, before accidentally kicking her out of bed.

The Art of Seduction in 'The Brain Bowl Incubation'

Season 10, Episode 8

Original Airdate: Nov. 10, 2016

As hard as Sheldon is to resist, Amy is not willing to have children just for the sake of science.

Princeton Proposal in 'The Long Distance Dissonance'

Season 10, Episode 24

Original Airdate: May 11, 2017

Sheldon flies to cross country to propose to Amy. It doesn't get much more romantic than that.

Quickie Wedding Cancelled in 'The Confidence Erosion'

Season 11, Episode 10

Original Airdate: Dec. 10, 2017

Sheldon realizes all that he and Amy would be giving up if they get hitched at City Hall, including a proper first dance as husband and wife.

Saying 'I Do' in 'The Bow Tie Asymmetry'

Season 11, Episode 24

Original Airdate: May 10, 2018

The longtime couple ties the knot in a ceremony officiated by Mark Hamill — but not before reaching a scientific breakthrough that'll change the course of their lives.

Nobel Prize Win in 'The Stockholm Syndrome'

Season 12, Episode 24

Original Airdate: May 16, 2019

The marrieds' breakthrough in super asymmetry lands them on stage in Stockholm, where Sheldon delivers a poignant, series-ending acceptance speech.

Son's Name Revealed on Young Sheldon

Season 4, Episode 1

Original Airdate: Nov. 5, 2020

As the Cooper family gathered to commemorate Sheldon's graduation from high school, Sheldon the Narrator (voiced by Jim Parsons) said that "it was the best graduation party I had been to... until we had one for my son, Leonard Cooper. I wanted his name to be Leonard Nimoy Cooper, but Amy wouldn't let me," he revealed. That's when Mayim Bialik chimed in as Sheldon's better half and said, "Be lucky I let you name him Leonard." (For a running list of Young Sheldon Easter eggs, click here.)

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